Show this safety data sheet to the doctor in attendance. Methylparaben and propylparaben are the most common of these. In addition, for the pharmaceutical industry, methylparaben can be used as an antiseptic agent. Pdf determination of methylparaben from cosmetic products. Structure, properties, spectra, suppliers and links for. Methyl paraben, methyl paraben supplier, methyl paraben distributor, cas 99763, methyl paraben manufacturer, methyl paraben wholesale.
Methylparaben is an antifungal and preservative that is widely used in cosmetics. Sodium methylparaben e219 is a organic compound manufactured through chemical synthesis. To drosophila, methylparaben is toxic at higher concentrations, has an estrogenic effect mimicking estrogen in rats and having antiandrogenic activity, and slows the growth rate in the larval and pupal stages at lower concentrations. Besides, methylparaben is a kind of chemically inert material that leads it to have easy compatibility with a variety of chemical substances. Get a quick quote download product spec download sds. Tsca components tsca section 5a2 chemicals with significant new use rules snurs tsca 8d health and safety reporting methylparaben not applicable not applicable product code. Safety data sheets sections 1 through 8 contain general information about the chemical, identification, hazards, composition, safe handling practices, and emergency control measures e. Buy methyl paraben cas 99763, an analytical reagent for sterol.
Other companies are charging thousands of dollars to set up. Other companies are charging thousands of dollars to set up accounts and. The resource to the url or file is currently unavailable. Methylparaben ingredient for cosmetics formulations find latest products launched and their applications in relevant industry news and technical articles. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only.
Safety data sheets free sds database chemical safety. Box 194 old bridge, new jersey 08857 telephone 732 7272225 emergency telephone 1800 2753924. Methylparaben msds,methylparaben materials safety data sheet. Methylparaben has been used as a preservative in the food, cosmetic, and pharmaceutical industries for over 50 years. It is the most frequently used antimicrobial preservative in cosmetics. The analysis were carried out on a reversedphase c 18 column 250 x 4. Methylparaben degraded 100% after 6 days with a 2 day acclimation period in sludge inoculum using the zahnwellens test1 which requires a 0. If inhaled if breathed in, move person into fresh air. Typically, this chemical will be formulated into creams and serums with other parabens, like butylparaben and propylparaben, though in some cases it may be used on a standalone basis. Sodium methylparaben msds, sodium methylparaben materials.
Preservative chemical description methylparaben download specs and sds specs sds. Easily soluble in alcohol, ether and acetone, slightly soluble in water. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure. Lush buy methylparaben and propylparaben from a company that has sustainable principles and recycles water and power as much as possible. First aid measures general advice consult a physician.
Combined activation of methylparaben by sunlight irradiation and skin esterases lead toward oxidative dna damage. Sodium methylparaben msds manufacturers, sodium methylparaben suppliers, sodium. Preparation of solutions for validation study standard solutions for linearity study. Sharon laboratories is a global manufacturer of solutions for preserving and prolonging the shelf life of personal care products, and is an industry leader in development, production and marketing for preservatives. Ewg s skin deep database gives you practical solutions to protect yourself and your family from everyday exposures to chemicals in personal care products. We make no warranty of merchantability or any other warranty, express or implied, with respect to. Files available from the acs website may be downloaded for. Preservetaves are required in makeup to prevent microbial growth. In short, methylparaben product is the most ideal and efficient preservative in daily chemical industry. The crystal structure of methyl paraben polymorph ii is similar to the layered. Poison information centres in each state capital city can provide additional assistance for scheduled poisons 1126 skin contact. Methylparaben, also methyl paraben, one of the parabens, is a preservative with the chemical. Based on this data methylparaben is expected to biodegrade readily in the environmentsrc.
Spectrum chemical nf products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities. Methyl 4hydroxybenzoate msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available. We ask that users who download significant portions of the database cite the hmdb paper in any resulting publications. Methylparaben is a 4hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4hydroxybenzoic acid with methanol. Safety data sheet methyl 4hydroxybenzoate bp grade.
Methylparaben is the ester of methyl alcohol and phydroxybenzoic acid. To drosophila, methylparaben is toxic at higher concentrations, has an estrogenic effect mimicking estrogen in rats and having antiandrogenic activity, and slows the growth rate in the larval. Antimicrobial cosmetics and personal care products. The information in this methylparaben e218 msds was obtained from current and reliable sources. Identification product identifier product name cosepttm pep other means of identification product code 0367 synonyms methylparaben, ethylparaben, butylparaben, isobutylparabenand propylparaben in phenoxyethanol recommended use of the chemical and restrictions on use. Methyl paraben cas 99763 scbt santa cruz biotechnology. The product has been classified and labeled in accordance with ec directivesordinance on hazardous materials chip code letter hazard designation of product. Pdf determination of methylparaben from cosmetic products by. It can be refined by the means of esterification catalyzed by sulfuric acid of phydroxybenzoic acid and methanol. Mixtures of the parabens, such as methylparaben and propylparaben, allow for much smaller amounts of the chemical to be used.
Parabens are most common in personal care products that contain significant amounts of water such as shampoos, conditioners, lotions and facial and shower cleansers and scrubs because they discourage the growth of microbes. Download sds msds region certificate of analysis catalog. Methylparaben, nf is an excipient used as a preservative. A safety data sheet, or sds, is a standardized document that contains occupational safety and health data. Methylparaben is a constituent of cloudberry, yellow passion fruit, white wine, botrytised wine and bourbon vanill.
Wash off immediately with soap and plenty of water removing all contaminated clothes and shoes. Methyl 4hydroxybenzoate cas 99763 106757 emd millipore. Methylparaben belongs to the paraben family of ingredients, which all act as preservatives in skin care products. It occurs naturally in several fruits, particularly in blueberries. Sodium methylparaben is a organic compound manufactured through chemical synthesis. Methylparaben, ethylparaben, propylparaben, butylparaben, isobutylparaben, phenoxyethanol. Methylparaben united states pharmacopeia usp reference standard synonym. Methylparaben e218 is fully biodegradable and the products of degradation are not toxic.
Identification product identifier product name cosepttm pep other means of identification product code 0367 synonyms methylparaben, ethylparaben, butylparaben, isobutylparabenand propylparaben in. Crystal structure of methyl paraben polymorph ii crystal growth. Material safety data sheet sodium methylparaben msds 1. Parabens mimic estrogen and can act as potential hormone endocrine sys. However, the data is provided without any warranty, expressed or implied, regarding its correctness or accuracy. The information in this sodium methylparaben e219 msds was obtained from current and reliable sources. Parabens have been used since the 1920s in food and cosmetics preservation. Because it is easily absorbed through the skin and is generally considered nonirritating, it is a very popular beauty product ingredient wikpedia and is used to prevent fungal growth and to generally preserve formulas. Methylparaben is in the paraben family of preservatives used by the food, pharmaceutical, and personal care product industries.
Scientific committee on consumer safety sccs opinion on parabens, colipa n p82. Buy methyl paraben cas 99763, an analytical reagent for sterol hormone studies, from santa cruz. Sds of methylparaben, safety data sheets, cas 99763. Methylparaben 99763 manufacturerlow pricehigh qualityin stock. Download product safety card request more information about this product. Material safety data sheet common name copper sulfate manufacturer old bridge chemicals, inc. Refer to certificate of analysis for lot specific data including water. Parabens as preservatives in personal care products. Solubilization of methylparaben in nonionic surfactant micelles in aqueous solution.
Methyl paraben persistence and degradability may cause longterm adverse effects in the environment. The international hazard communication standard hcs mandates that chemical manufacturers must communicate a chemicals hazard information to chemical handlers by providing a safety data sheet. Bioaccumulative potential methyl paraben log pow 1. Methylparaben is commonly used as a fungicide in drosophila food media. This information should be helpful to those that need to get the information quickly. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Sds of methylparaben, safety data sheets, cas 99763 chemblink.
Methyl phydroxybenzoate 99763 persistence and degradability readily biodegradable, according to appropriate oecd test. Sharon laboratories is a global manufacturer of solutions for preserving and prolonging the shelf life of personal care products, and is an industry leader in development, production and. Comparison of the global gene expression profiles produced by methylparaben, nbutylparaben and 17betaoestradiol in mcf7 human breast cancer cells, j appl toxicol. Relevant identified uses of the substance or mixture and uses advised against identified uses laboratory reagent. Pdf parabens as preservatives in personal care products.
Applications of methylparaben methylparaben also called as nipagin is white crystalline powder. Wash off immediately with soap and plenty of water removing all contaminated clothes. Determination of methylparaben from cosmetic products by ultra performance liquid chromatography article pdf available in journal of the serbian chemical society 746 june 2009 with 689 reads. Acidity to 2 ml of methylparaben solution prepared in the color of solution test add 3 ml of alcohol, 5 ml of carbon dioxidefree water, and 0. Pdf a new method for the determination of methylparaben by ultraperformance liquid chromatography uplc was. It is a fine crystalline powder, which is odourless, tasteless and nonirritating. This structure is also available as a 2d mol file or as a computed 3d sd file. Material safety data sheet sodium methyl paraben october 10, 2012 page 5 of 5 regulatory information ec guidelines designation. Enter synonyms, trade names or additional information found in section 1. M8911 lot 114k8801 infrared spectrum mineral oil dispersion wavenumbers cm1 ho ch3 o 4000 3600 3200 2800 2400 2000 1600 1200 800 400 20. This information should be helpful to those that need to. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Safety data sheet issue date 01may2015 revision date 27feb2015 version 1 1. Solubilization of methylparaben in nonionic surfactant micelles in.
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